Abstract
Atopic dermatitis (AD) is a chronic relapsing skin disease which affects 15%‐20% of children worldwide.1 It is also considered as a major risk factor for developing other atopic diseases including food allergy, asthma, and allergic rhinitis later in life—a phenomenon known as the “atopic march.” Multiple factors, including season of birth and associated perinatal environmental conditions, have been known to play important roles in the manifestation of AD.2 Moreover, about 20% of patients with AD have moderate‐to‐severe disease, which is associated with significantly lower quality of life, imposing considerable burden on the nation’s health‐care resources.3 Therefore, studying severe AD patients might be very important in managing overall AD‐related disease burden. The objective of the present study was to identify potential birth season(s) associated with severe AD in Armenian pediatric patients, which would be helpful for the country’s health‐care researchers working toward identifying potential factors associated with severe pediatric AD in Armenia.