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ChemInform Abstract: Acceleration of the Morita-Baylis-Hillman Reaction by a Simple Mixed Catalyst System
Journal article

ChemInform Abstract: Acceleration of the Morita-Baylis-Hillman Reaction by a Simple Mixed Catalyst System

Alejandro Bugarin and Brian T Connell
ChemInform, Vol.40(44), pp.no-no
11-03-2009
PMID: 19449847

Abstract

alcohols (benzene compounds) cyclopentane derivatives furan derivatives thiophene derivatives xanthene derivatives
By using a catalytic amount of 4-dimethylaminopyridine (DMAP) as a nucleophile in the presence of an equal amount of tetramethylethylenediamine (TMEDA) and MgI2, Morita−Baylis−Hillman adducts can be obtained in good to excellent yields from various aromatic and aliphatic aldehydes and cyclic enones/enoates at room temperature after convenient reaction times.
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