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Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia
Journal article   Open access   Peer reviewed

Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia

Kristi L Watterberg, Michele C Walsh, Lei Li, Sanjay Chawla, Carl T D’Angio, Ronald N Goldberg, Susan R Hintz, Matthew M Laughon, Bradley A Yoder, Kathleen A Kennedy, …
The New England journal of medicine, Vol.386(12), pp.1121-1131
03-23-2022
PMID: 35320643

Abstract

Critical Care General Growth and Development Hospital-Based Clinical Medicine Mechanical Ventilation Neurosurgery General Pediatrics General Pulmonary Clinical Medicine Critical Care Neonatology Neurology Neurosurgery Pediatrics
Glucocorticoids might prevent bronchopulmonary dysplasia in extremely preterm infants but have adverse neurodevelopmental effects. In this trial involving preterm infants, there was little difference in survival without bronchopulmonary dysplasia or in the occurrence of neurodevelopmental impairment with hydrocortisone as compared with placebo.
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