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In vitro dynamic swelling behaviors of radiation synthesized polyacrylamide with crosslinkers in the simulated physiological body fluids
Journal article   Peer reviewed

In vitro dynamic swelling behaviors of radiation synthesized polyacrylamide with crosslinkers in the simulated physiological body fluids

Dursun Saraydın, Yasemin Işıkver, Erdener Karadağ, Nurettin Sahiner and Olgun Güven
Nuclear instruments & methods in physics research. Section B, Beam interactions with materials and atoms, Vol.187(3), pp.340-344
03-01-2002

Abstract

Acrylamide Biomaterials Hydrogel Ionizing radiation Simulated body fluids
Acrylamide hydrogels, containing different amounts and types of crosslinkers, were synthesized via γ-irradiation technique. Their swellings in simulated body fluids, such as physiological saline (0.89% NaCl) isoosmotic phosphate buffer at pH 7.4, gastric fluid at pH 1.1 (glycine–HCl), protein (aqueous solution of bovine serum albumin), urine (aqueous solution of urea), glucose and distilled water, were studied. Equilibrium swellings of the hydrogels were changed in the range 27–85 depending upon the fluids, type and amount of crosslinkers. The diffusion exponents were found over half for all hydrogels.
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