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Metabolism of diethylene glycol in male rats
Journal article   Peer reviewed

Metabolism of diethylene glycol in male rats

Harvey L. Wiener and Keith E. Richardson
Biochemical pharmacology, Vol.38(3), pp.539-541
02-01-1989
PMID: 2917011

Abstract

Excerpt: Various incidents of diethylene glycol (2,2'-oxybisethanol; DEG) poisoning have occurred throughout the world [1-4]. Little is known about the metabolism and the mechanism of toxicity of DEG, a common industrial solvent that has recently been used illegally to sweeten wine. DEG has been suggested [5, 6] to follow the same metabolic pathway as ethylene glycol (EG), although this has not been demonstrated experimentally. (cont.)
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