Setting research priorities to improve global newborn health and prevent stillbirths by 2025

Sachiyo Yoshida; Jose Martines; Joy E. Lawn; Stephen Wall; Joao Paulo Souza; Igor Rudan; Simon Cousens; Peter Aaby; Ishag Adam; Ramesh Kant Adhikari; Namasivayam Ambalavanan; Shams El Arifeen; Dhana Raj Aryal; Sk Asiruddin; Abdullah Baqui; Aluisio J. D. Barros; Christine S. Benn; Vineet Bhandari; Shinjini Bhatnagar; Sohinee Bhattacharya; Zulfiqar A. Bhutta; Robert E. Black; Hannah Blencowe; Carl Bose; Justin Brown; Christoph Buehrer; Wally Carlo; Jose Guilherme Cecatti; Po-Yin Cheung; Robert Clark; Tim Colbourn; Agustin Conde-Agudelo; Erica Corbett; Andrew E. Czeizel; Abhik Das; Louise Tina Day; Carolyn Deal; Ashok Deorari; Ugur Dilmen; Mike English; Cyril Engmann; Fabian Esamai; Caroline Fall; Donna M. Ferriero; Peter Gisore; Tabish Hazir; Rosemary D. Higgins; Caroline S. E. Homer; D. E. Hoque; Lorentz Irgens; M. T. Islam; Joseph de Graft-Johnson; Martias Alice Joshua; William Keenan; Soofia Khatoon; Helle Kieler; Michael S. Kramer; Eve M. Lackritz; Tina Lavender; Laurensia Lawintono; Richard Luhanga; David Marsh; Douglas McMillan; Patrick J. McNamara; Ben Willem J. Mol; Elizabeth Molyneux; G. K. Mukasa; Miriam Mutabazi; Luis Carlos Nacul; Margaret Nakakeeto; Indira Narayanan; Bolajoko Olusanya; David Osrin; Vinod Paul; Christian Poets; Uma M. Reddy; Mathuram Santosham; Rubayet Sayed; Natalia E. Schlabritz-Loutsevitch; Nalini Singhal; Mary Alice Smith; Peter G. Smith; Sajid Soofi; Catherine Y. Spong; Shahin Sultana; Antoinette Tshefu; Frank van Bel; Lauren Vestewig Gray; Peter Waiswa; Wei Wang; Sarah L. A. Williams; Linda Wright; Anita Zaidi; Yanfeng Zhang; Nanbert Zhong; Isabel Zuniga; Rajiv Bahl; Neonatal Hlth Res Priority Setting

doi:10.7189/jogh.06.010508

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Setting research priorities to improve global newborn health and prevent stillbirths by 2025

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Setting research priorities to improve global newborn health and prevent stillbirths by 2025

Sachiyo Yoshida, Jose Martines, Joy E. Lawn, Stephen Wall, Joao Paulo Souza, Igor Rudan, Simon Cousens, Peter Aaby, Ishag Adam, Ramesh Kant Adhikari, …

Journal of global health, Vol.6(1), pp.010508-010508

06-01-2016

DOI: https://doi.org/10.7189/jogh.06.010508

PMCID: PMC4576458

PMID: 26401272

Abstract

Life Sciences & Biomedicine

Public, Environmental & Occupational Health

Science & Technology

Background In 2013, an estimated 2.8 million newborns died and 2.7 million were stillborn. A much greater number suffer from long term impairment associated with preterm birth, intrauterine growth restriction, congenital anomalies, and perinatal or infectious causes. With the approaching deadline for the achievement of the Millennium Development Goals (MDGs) in 2015, there was a need to set the new research priorities on newborns and stillbirth with a focus not only on survival but also on health, growth and development. We therefore carried out a systematic exercise to set newborn health research priorities for 2013-2025. Methods We used adapted Child Health and Nutrition Research Initiative (CHNRI) methods for this prioritization exercise. We identified and approached the 200 most productive researchers and 400 program experts, and 132 of them submitted research questions online. These were collated into a set of 205 research questions, sent for scoring to the 600 identified experts, and were assessed and scored by 91 experts. Results Nine out of top ten identified priorities were in the domain of research on improving delivery of known interventions, with simplified neonatal resuscitation program and clinical algorithms and improved skills of community health workers leading the list. The top 10 priorities in the domain of development were led by ideas on improved Kangaroo Mother Care at community level, how to improve the accuracy of diagnosis by community health workers, and perinatal audits. The 10 leading priorities for discovery research focused on stable surfactant with novel modes of administration for preterm babies, ability to diagnose fetal distress and novel tocolytic agents to delay or stop preterm labour. Conclusion These findings will assist both donors and researchers in supporting and conducting research to close the knowledge gaps for reducing neonatal mortality, morbidity and long term impairment. WHO, SNL and other partners will work to generate interest among key national stakeholders, governments, NGOs, and research institutes in these priorities, while encouraging research funders to support them. We will track research funding, relevant requests for proposals and trial registers to monitor if the priorities identified by this exercise are being addressed

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Title: Setting research priorities to improve global newborn health and prevent stillbirths by 2025
Creators: Sachiyo Yoshida - World Health Organization - Pakistan
Jose Martines - University of Bergen
Joy E. Lawn - University of London
Stephen Wall - Save the Children
Joao Paulo Souza - Universidade de São Paulo
Igor Rudan - University of Edinburgh
Simon Cousens - University of London
Peter Aaby - Bandim Health Project
Ishag Adam - University of Khartoum
Ramesh Kant Adhikari - Kathmandu Medical College Teaching Hospital
Namasivayam Ambalavanan - University of Alabama at Birmingham
Shams El Arifeen - Int Ctr Diar rhoeal Dis Res, Ctr Child & Adolescent Hlth, Dhaka, Bangladesh
Dhana Raj Aryal - Paropakar Matern & womens Hosp, Dept Neonatol, Kathmandu, Nepal
Sk Asiruddin - University Research Co (United States)
Abdullah Baqui - Johns Hopkins University
Aluisio J. D. Barros - Universidade Federal de Pelotas
Christine S. Benn - University of Southern Denmark
Vineet Bhandari - Yale University
Shinjini Bhatnagar - Translational Health Science and Technology Institute
Sohinee Bhattacharya - University of Aberdeen
Zulfiqar A. Bhutta - Aga Khan University
Robert E. Black - Johns Hopkins University
Hannah Blencowe - University of London
Carl Bose - University of North Carolina at Chapel Hill
Justin Brown - Thrasher Research Fund
Christoph Buehrer - Charles University
Wally Carlo - University of Alabama at Birmingham
Jose Guilherme Cecatti - Universidade Estadual de Campinas (UNICAMP)
Po-Yin Cheung - University of Alberta
Robert Clark - Charities, New Orleans, LA USA
Tim Colbourn - University College London
Agustin Conde-Agudelo - National Institutes of Health
Erica Corbett - Independent consultant maternal Hlth Res, Kigali, Rwanda
Andrew E. Czeizel - Fdn Commun Control Hereditary Dis, Budapest, Hungary
Abhik Das - RTI International
Louise Tina Day - LAMB Integrated Rural Hlth & Dev, Dinajpur, Bangladesh
Carolyn Deal - National Institutes of Health
Ashok Deorari - All India Institute of Medical Sciences
Ugur Dilmen - Ankara (Czechia)
Mike English - University of Oxford
Cyril Engmann - Gates Foundation
Fabian Esamai - Moi University
Caroline Fall - Univ Southampton, Med Res Council, Lifecourse Epidemiol Unit, Int Paediat Epidemiol, Southampton, Hants, England
Donna M. Ferriero - University of California, San Francisco
Peter Gisore - Moi University
Tabish Hazir - Pakistan Institute of Medical Sciences
Rosemary D. Higgins - National Institutes of Health
Caroline S. E. Homer - University of Technology Sydney
D. E. Hoque - Int Ctr Diarrhoeal Dis Res, Ctr Child & Adolescent Hlth, Dhaka, Bangladesh
Lorentz Irgens - University of Bergen
M. T. Islam - Japan International Cooperation Agency
Joseph de Graft-Johnson - Save the Children
Martias Alice Joshua - Zomba Cent Hosp, Minist Hlth, Zomba, Malawi
William Keenan - Saint Louis University
Soofia Khatoon - Shaheed Suhrawardy Medical College
Helle Kieler - Karolinska Institutet
Michael S. Kramer - McGill University
Eve M. Lackritz - Global Alliance Prevent Prematur & Stillbirth GAP, Seattle, WA USA
Tina Lavender - University of Manchester
Laurensia Lawintono - Indonesian Midw Assoc, Jakarta, Indonesia
Richard Luhanga - Save the Children
David Marsh - Save the Children
Douglas McMillan - Dalhousie University
Patrick J. McNamara - University of Toronto
Ben Willem J. Mol - University of Amsterdam
Elizabeth Molyneux - University of Malawi
G. K. Mukasa - ACT
Miriam Mutabazi - STRIDES Family Hlth, Management Sci Hlth, Kampala, Uganda
Luis Carlos Nacul - University of London
Margaret Nakakeeto - Boston Children's Hospital
Indira Narayanan - United States Agency for International Development
Bolajoko Olusanya - Healthy Start
David Osrin - University College London
Vinod Paul - All India Institute of Medical Sciences
Christian Poets - University of Tübingen
Uma M. Reddy - National Institutes of Health
Mathuram Santosham - Johns Hopkins University
Rubayet Sayed - Save the Children
Natalia E. Schlabritz-Loutsevitch - University of Tennessee Health Science Center
Nalini Singhal - University of Calgary
Mary Alice Smith - University of Georgia
Peter G. Smith - Supreme Council Of Health
Sajid Soofi - Aga Khan University
Catherine Y. Spong - National Institutes of Health
Shahin Sultana - Ministry of Health and Family Welfare
Antoinette Tshefu - University of Kinshasa
Frank van Bel - Utrecht University
Lauren Vestewig Gray - Rice University
Peter Waiswa - Karolinska Institutet
Wei Wang - Edith Cowan University
Sarah L. A. Williams - Edith Cowan University
Linda Wright - National Institutes of Health
Anita Zaidi - Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, NIH, Bethesda, MD USA
Yanfeng Zhang - Capital University
Nanbert Zhong - New York State Office for People With Developmental Disabilities
Isabel Zuniga - Médecins Sans Frontières
Rajiv Bahl - World Health Organization - Pakistan
Neonatal Hlth Res Priority Setting
Publication Details: Journal of global health, Vol.6(1), pp.010508-010508
Publisher: Univ Edinburgh, Global Health Soc; EDINBURGH
Number of pages: 10
Grant note: MC_UP_A620_1016 / Medical Research Council; UK Research & Innovation (UKRI); Medical Research Council UK (MRC); European Commission MC_UU_12011/3 / MRC; UK Research & Innovation (UKRI); Medical Research Council UK (MRC) Save the Children
Identifiers: 99383452085306570
Academic Unit: Office of Research & Sponsored Programs
Language: English
Resource Type: Journal article

Setting research priorities to improve global newborn health and prevent stillbirths by 2025

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