Abstract
This cross-sectional analysis identified demographic and sport-specific determinants of e-cigarette and vape use among 2,489 National Association of Intercollegiate Athletics student-athletes. Binary logistic regression modeled current e-cigarette and vaping status as a function of sport affiliation, race/ethnicity, and biological sex. The final model demonstrated strong fit (Nagelkerke R² = .41) and correctly classified 79.7 percent of cases. Sport affiliation emerged as the strongest predictor. Race/ethnicity and biological sex further differentiated risk, with male and White athletes exhibiting elevated prevalence. Collectively, the results underscore the potency of team culture and demographic context in shaping nicotine behaviors. Findings advocate for sport-tailored, culturally responsive, and biological sex-specific prevention initiatives. These initiatives, integrated with comprehensive campus tobacco-free policies, could protect health and performance across collegiate athletics.